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By K.-D. Kohl, W. Sperling (auth.), Professor Dr. Gerold Adam, Professor Dr. Günther Stark (eds.)

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Additional resources for Annual Meeting of the Deutsche Gesellschaft für Biophysik: Konstanz, October 1979. Abstracts of Poster Presentations

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Sackmann Universitat Ulm Abteilung Experimentelle Physik III Oberer Eselsberg D-7900 Ulm (Donau) Macroscopically ordered mUltibilayers of dipalmitoyl phosphatidylcholine (DPPC) and dioleoyl phosphatidylcholine (DOPC) with a thickness of up to 200 pm are prepared by a temper process. The water content is varied up to 20 weight % by controlling the external humidity and is measured by infrared spectroscopy. EPR spin label spectroscopy using nitroxide fatty acid labels as well as nitroxide lecithin labels gives a phase diagram of these thermotropic and lyotropic smectic liquid crystals.

B20 42 SURFACE POTENTIAL STUDIES OF MONOLAYERS FROM DIFFERENT STEROLS AND VARIOUS PHOSPHOLIPID/STEROL MIXTURES. P. Jauch, A. Hermetter+, F. Paltauf+ and R. Benz, Fachbereich Biologie, Universitat Konstanz, D-7750 Konstanz and +Institut fUr Biochemie, Technische Universitat Graz, A-BOlO Graz A surface potential instrumentation was constructed in order to measure simultaneously surface potential as well as surface pressure of monolayers as a function of the area of the molecules. Monolayers from sterols with a 3-8 hydroxy group (cholesterol, 7-dehydrocholesterol, stigmasterol and ergosterol) showed potentials between 400 and 475 mV at 30 dyn/cm.

Experiments with lipid monolayers in the presence of local anesthetic show that the surface potential is reduced by more than 100 mV. This finding is so far consistent with the above mentioned suggestion that local anesthetics reduce the dipolar potential of membranes. [11 Benz, R. , J. Membrane BioI. , Biochim. Biophys. Acta 455, 701 ~] McLaughlin, S. in Progress in Anesthesiology, Vol. Y. 1975, p. 193 B23 45 NEGATIVE HYDROPHOBIC IONS AS CARRIERS FOR POSITIVE HYDROPHOBIC IONS G. Stark Fakultat fur Biologie, Universitat Konstanz, D-7750 Konstanz The permeability of positively charged hydrophobic ions across biological membranes and artificial lipid membranes is strongly increased in the presence of trace amounts of negative hydrophobic ions (1).

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